Brain implant can rewire epilepsy research🧠
In a newly published cutting-edge study, a team led by group leader Christos Markos showcase how we interact with the brain to understand and treat neurological disorders with focus on epilepsy🔬
Epilepsy is a complex neurological condition affecting millions worldwide, characterized by recurrent, unpredictable seizures.
Detecting the onset and propagation of seizures, and understanding the neural circuitry that underlies them, remains a central challenge in both research and clinical practice🩺
This study introduces a novel flexible microfluidic neural interface; a soft, multimodal device that integrates optical, electrical, and chemical sensing and stimulation capabilities into a single polymer-based neural interface, which can:
⚡Record electrical signals across brain layers with high precision
🎯Deliver targeted optical stimulation to modulate neural activity
🧪Deliver and sample chemicals to probe neurochemical changes
🔎Achieve multimodal interrogation of brain mechanisms contributing to seizure initiation and spread
These capabilities can dramatically improve our understanding of epileptic circuits, potentially leading to better diagnostics, more effective closed-loop therapies, and personalized intervention strategies.
Find the paper in the here!
This work was supported by the Lundbeckfonden / Lundbeck Foundation and the project Multi-BRAIN as well as Project Move2Treat – EU HORIZON EIC 2024 PATHFINDER OPEN.
